Southern Style Meatloaf 

Prep Time: 10 minutes | Cook Time: 70 minutes



  • Meatloaf
  • 2 lbs ground beef, chuck or 85% work best
  • 2 tbs butter, olive oil, or bacon drippings
  • 1 onion, finely chopped
  • 1/2 bell pepper, finely chopped (Optional but tasty!)
  • 2 cloves garlic, minced
  • 1/2 cup ketchup
  • 2 tsp Worcestershire sauce
  • 1 cup Italian flavored bread crumbs
  • 1 tsp cajun seasoning
  • 1/2 tsp paprika
  • 1 pinch dry mustard
  • 2 large eggs, beaten
  • Salt and pepper, to taste
  • Sauce
  • 1/2 cup ketchup
  • 1 tbs mustard
  • 1 tbs brown sugar, packed
  • 2 tsp Worcestershire sauce


Preheat oven to 350 F.

Heat a skillet over medium with butter then cook the onion and bell pepper until they begin to soften and caramelize, about 7-10 minutes. Add garlic and cook for 1 minute more, then remove from heat and set aside to let cool until cool enough to touch.

In a large mixing bowl, combine ground beef, ketchup, Worcestershire sauce, bread crumbs, Cajun seasoning, paprika, dry mustard, and eggs. Add cooled sautéed vegetables and stir to incorporate.

Press mixture into a 9 x 5 or 10 x 5 loaf pan, avoiding overworking the meat.

Whisk together the sauce ingredients, then spoon it over the top.

Bake until internal temperature reaches 160 F, about 1 hour.


Roast some carrots alongside the meatloaf and serve with mashed potatoes, and you've got a star of a meal.

Nutrition Facts
Southern Style Meatloaf
Amount Per Serving
Calories 396 Calories from Fat 243
% Daily Value*
Total Fat 27g 42%
Saturated Fat 9g 45%
Polyunsaturated Fat 1g
Monounsaturated Fat 13g
Cholesterol 106mg 35%
Sodium 788mg 33%
Potassium 523mg 15%
Total Carbohydrates 15g 5%
Dietary Fiber 1g 4%
Sugars 10g
Protein 22g 44%
Vitamin A 21%
Vitamin C 69%
Calcium 2%
Iron 15%
* Percent Daily Values are based on a 2000 calorie diet.